Key notes

  • Keynote 1:

Multimodality molecular imaging: Paving the way for personalized medicine

Prof. Habib Zaidi1,2,3,4

1Division of Nuclear Medicine and Molecular Imaging, Geneva University Hospital, Switzerland

2Department of Nuclear Medicine and Molecular Imaging, University of Groningen, The Netherlands

3Department of Nuclear Medicine, University of Southern Denmark, Odense, Denmark

4Institute for Advanced Studies, University of Cergy-Pontoise, Cergy, France

Email: habib.zaidi@hcuge.ch

Web:   http://pinlab.hcuge.ch/

 

Abstract

 Early diagnosis and therapy increasingly operate at the cellular, molecular or even at the genetic level. As diagnostic techniques transition from the systems to the molecular level, the role of multimodality molecular imaging becomes increasingly important. Positron emission tomography (PET), x-ray CT and MRI are powerful techniques for in vivo imaging. The inability of PET to provide anatomical information is a major limitation of standalone PET systems. Combining PET and CT proved to be clinically relevant and successfully reduced this limitation by providing the anatomical information required for localization of metabolic abnormalities. However, this technology still lacks the excellent soft-tissue contrast provided by MRI. Standalone MRI systems reveal structure and function, but cannot provide insight into the physiology and/or the pathology at the molecular level. The combination of PET and MRI, enabling truly simultaneous acquisition, bridges the gap between molecular and systems diagnosis. MRI and PET offer richly complementary functionality and sensitivity; fusion into a combined system offering simultaneous acquisition will capitalize the strengths of each, providing a hybrid technology that is greatly superior to the sum of its parts.

This talk also reflects the tremendous increase in interest in quantitative molecular imaging using PET as both clinical and research imaging modality in the past decade. It offers a brief overview of the entire range of quantitative PET imaging from basic principles to various steps required for obtaining quantitatively accurate data from dedicated standalone PET and combined PET/CT and PET/MR systems including algorithms used to correct for physical degrading factors and to quantify tracer uptake and volume for radiation therapy treatment planning. Future opportunities and the challenges facing the adoption of multimodality imaging technologies and their role in biomedical research will also be addressed.

  • Keynote 2:

CRITICAL LITERATURE REVIEW: PREPARATION STRATEGIES

Prof SYED TAJUDDIN BIN SYED HASSAN, Dr Saliza Mohd Elias, Dr. Md Jalalian Mehrdad

ABSTRACT

The imperative needs for, and characteristics of an effective critical literature review, provide the foreground baseline deliberation. A visual model depicting synthesized major modular components of a research project delineate impact points of literature review inputs.  The three major modules represent preparation, data capture, and data rendering-analysis-interpretation phases of research. Within each module, the literature review elements to be incorporated are elaborated. Steps and optimal articulation-action strategies are highlighted and embedded with examples from literature and theses. Development of competency and efficacy in critiquing and evaluating, which comprised mandatory skills to acquire, is especially focussed.

 

Prof SYED TAJUDDIN BIN SYED HASSAN Department of Nursing and Rehabilitation, Faculty of Medecine and Health sciences, University Putra Malaysia.

Dr Saliza Mohd Elias PhD, Department of Environmental and Occupational Health, Faculty of Medecine and Health sciences, University Putra Malaysia.

Dr. Md Jalalian Mehrdad, Director, Mehrafarin Scientific Publishing,Kish Island, Iran. Editor-in cheif of Electronic Physician Journal, Mashhad, Iran.

 

  • Keynote 3:

RESEARCH EXCELLENCE: THE IMPERATIVE PRIMERS

Prof SYED TAJUDDIN BIN SYED HASSAN, Dr Saliza Mohd Elias, Dr. Md Jalalian Mehrdad

ABSTRACT

 Research excellence characteristics are comprehensively delineated, encompassing creativity through transnationality and translation-capability. The research iterative primers of “Re” and “search” as the underlying push-engine, is briefly illustrated. Subsequently, a visual model depicting three major modules of the entire research task-process illustrates the need to balance the preparation and the rendition of data and interpretation components, through the mediating role of data capture. Traits of the primers characterising research excellence are consequently deliberated and discussed thoroughly using the acronym R-E-S-E-A-R-C-H. The initial three entities, RES, fittingly portray the literature review matrix; with reviewing of references through examining “slacks” or gaps in available literature. The E is then envisaged as representing exclusivity through ethical considerations; A as audience through imbibition of overt and covert objectives, to audit trail analysis; R as rationale through research frame (interpretive, analytical, simulative); C as encompassing creativity through coherence (tone, voice, style); and, H as the human factors- trailing from biases through needs/wants to influences. Optimising values of these primers are deemed imperative to achieve excellence in a research project process and outcome.

 

Prof SYED TAJUDDIN BIN SYED HASSAN Department of Nursing and Rehabilitation, Faculty of Medecine and Health sciences, University Putra Malaysia.

Dr Saliza Mohd Elias PhD, Department of Environmental and Occupational Health, Faculty of Medecine and Health sciences, University Putra Malaysia.

Dr. Md Jalalian Mehrdad, Director, Mehrafarin Scientific Publishing,Kish Island, Iran. Editor-in cheif of Electronic Physician Journal, Mashhad, Iran.